听力与言语-语言病理学

行为科学

医学伦理学

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  • Participation of prefrontal neurons in the preparation of visually guided eye movements in the rhesus monkey.

    abstract::1. We recorded from 257 neurons in the banks of the posterior third of the principal sulcus of two rhesus monkeys trained to look at a fixation point and make saccades to stimuli in the visual periphery. Sixty-six percent (220/257) discharged or were suppressed in association with one or more aspects of the tasks we u...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.61.5.1064

    authors: Boch RA,Goldberg ME

    更新日期:1989-05-01 00:00:00

  • Functional properties of monkey caudate neurons. I. Activities related to saccadic eye movements.

    abstract::1. We recorded single cell activities in the caudate nucleus of the monkeys trained to perform a series of visuomotor tasks. In the first part of this paper, we summarize the types and locations of neurons in the monkey caudate nucleus. In the second part, we report the characteristics of neurons related to saccadic e...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.61.4.780

    authors: Hikosaka O,Sakamoto M,Usui S

    更新日期:1989-04-01 00:00:00

  • Memory traces in primate spinal cord produced by operant conditioning of H-reflex.

    abstract::1. Study of memory traces in higher animals requires experimental models possessing well-localized and technically accessible memory traces--plasticity responsible for behavioral change, not dependent on control from elsewhere, and open to detailed investigation. Our purpose has been to develop such a model based on t...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.61.3.563

    authors: Wolpaw JR,Lee CL

    更新日期:1989-03-01 00:00:00

  • Activity-dependent disinhibition. III. Desensitization and GABAB receptor-mediated presynaptic inhibition in the hippocampus in vitro.

    abstract::1. Single-electrode voltage-clamp recordings were made from CA3 pyramidal cells in organotypic hippocampal slice cultures for measurement of membrane currents underlying both the gamma-aminobutyric acid (GABA)-mediated, Cl- -dependent inhibitory postsynaptic potential (IPSC), evoked in response to stimulation of the m...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.61.3.524

    authors: Thompson SM,Gähwiler BH

    更新日期:1989-03-01 00:00:00

  • Effects of baclofen on transient neurons in the mudpuppy retina: electrogenic and network actions.

    abstract::1. Baclofen increases transient light responses of amacrine and ganglion cells despite acting as a classical inhibitory transmitter to both hyperpolarize and shunt these cells. 2. This effect seems to occur at the level of the inner retina and appears not to be due to an additional input from bipolar cells. 3. In some...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.61.2.382

    authors: Bai SH,Slaughter MM

    更新日期:1989-02-01 00:00:00

  • Deficits of visual attention and saccadic eye movements after lesions of parietooccipital cortex in monkeys.

    abstract::1. Visual attention is often profoundly disturbed in humans after damage to the cortex of the posterior parietal lobe, particularly of the minor hemisphere, with some patients being totally unaware of visual stimuli in the hemifield of extrapersonal space contralateral to the cortical damage. This severe form of visua...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.61.1.74

    authors: Lynch JC,McLaren JW

    更新日期:1989-01-01 00:00:00

  • Spinocervical tract neurons responsive to light mechanical stimulation of the raccoon forepaw.

    abstract::1. The extracellular activity of 45 antidromically identified spinocervical tract (SCT) neurons responsive to light mechanical stimulation of the glabrous surfaces of the forepaw was examined in raccoons anesthetized with pentobarbital sodium. An additional seven neurons had peripheral receptive fields (RFs) located o...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1989.61.1.138

    authors: Hirata H,Pubols BH Jr

    更新日期:1989-01-01 00:00:00

  • The accessory optic system of rabbit. I. Basic visual response properties.

    abstract::1. The response properties of accessory optic system (AOS) neurons were assessed using single-unit extracellular recording from each of the three AOS terminal nuclei [medial, lateral, and dorsal terminal nuclei (MTN, LTN, and DTN)] in the anesthetized rabbit. 2. AOS neurons had large, monocular (contralateral) recepti...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.6.2037

    authors: Soodak RE,Simpson JI

    更新日期:1988-12-01 00:00:00

  • The development of transmission at an identified molluscan synapse. II. A quantal analysis of transmission.

    abstract::1. A quantal analysis of transmission at the identified molluscan synapse, V2-RPr1, was performed during development. The study was intended to determine the pre- and postsynaptic contributions to the marked changes in transmitter release described in the previous report. 2. The success of the quantal analysis was pre...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.6.2211

    authors: Pawson PA,Chase R

    更新日期:1988-12-01 00:00:00

  • Nociceptive body representation in nucleus ventralis posterolateralis of cat thalamus.

    abstract::1. The somatotopic organization of nociceptive-specific (NS) and wide dynamic range (WDR) units in the nucleus ventralis posterolateralis (VPL) of the ventrobasal (VB) complex was studied. Experiments were carried out on adult cats anesthetized with urethane-chloralose. The recording sites of nociceptive units were ma...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.5.1714

    authors: Yokota T,Asato F,Koyama N,Masuda T,Taguchi H

    更新日期:1988-11-01 00:00:00

  • Response of vestibular neurons to head rotations in vertical planes. II. Response to neck stimulation and vestibular-neck interaction.

    abstract::1. We have studied the responses of neurons in the lateral and descending vestibular nuclei of decerebrate cats to stimulation of neck receptors, produced by rotating the body in vertical planes with the head stationary. The responses to such neck stimulation were compared with the responses to vestibular stimulation ...

    journal_title:Journal of neurophysiology

    pub_type: 临床试验,杂志文章

    doi:10.1152/jn.1988.60.5.1765

    authors: Kasper J,Schor RH,Wilson VJ

    更新日期:1988-11-01 00:00:00

  • Single-unit activity in bulbar reticular formation during food ingestion in chronic cats.

    abstract::1. Single-unit activity was recorded from 215 neurons in the medial bulbar reticular formation during the masticatory sequence, from intake to deglutition, of 3 kinds of food (cat food pellets, canned fish, and milk) in 8 chronically prepared, unanesthetized, spontaneously respiring cats with their head fixed to a ste...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.4.1333

    authors: Hiraba K,Taira M,Sahara Y,Nakamura Y

    更新日期:1988-10-01 00:00:00

  • Local superfusion modifies the inward rectifying potassium conductance of isolated retinal horizontal cells.

    abstract::1. Horizontal cells were enzymatically and mechanically dissociated from the white perch (Roccus americana) retina and voltage clamped using patch electrodes. Steady-state current-voltage (I-V) relationships of solitary horizontal cells were determined by changing the membrane potential in a rampwise fashion. 2. The I...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.4.1322

    authors: Perlman I,Knapp AG,Dowling JE

    更新日期:1988-10-01 00:00:00

  • Bipolar origin of synaptic inputs to sustained OFF-ganglion cells in the mudpuppy retina.

    abstract::1. The synaptic inputs to sustained OFF-center ganglion cells of the mudpuppy retina were studied using a superfused retina-eye-cup preparation. Intra- and extracellular electrophysiological recording techniques were carried out during bath application of 2-amino-4-phosphonobutyrate (APB), a glutamate analog that sele...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.3.1122

    authors: Arkin MS,Miller RF

    更新日期:1988-09-01 00:00:00

  • Computational study of an excitable dendritic spine.

    abstract::1. A compartmental model was employed to investigate the electrical behavior of a dendritic spine having excitable membrane at the spine head. Here we used the Hodgkin and Huxley equations to generate excitable membrane properties; in some cases the kinetics were modified to get a longer duration action potential. Pas...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.2.499

    authors: Segev I,Rall W

    更新日期:1988-08-01 00:00:00

  • Synaptic organization of the tectal-facial pathways in the cat. I. Synaptic potentials following collicular stimulation.

    abstract::1. The synaptic pathways underlying tectal influence over pinna movements were studied using an acute electrophysiological approach. Under pentobarbital anesthesia, postsynaptic potentials were recorded intracellularly in antidromically identified, cat facial motoneurons following electrical stimulation of the superio...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.2.769

    authors: Vidal PP,May PJ,Baker R

    更新日期:1988-08-01 00:00:00

  • Responses of rat lateral hypothalamic neuron activity to dorsal raphe nuclei stimulation.

    abstract::1. The effects of dorsal raphe (DR) stimulation on neural activity in the rat lateral hypothalamic area (LHA), including specific glucose-sensitive neurons, were investigated by extracellular and intracellular recording in vivo, and the neurotransmitters involved were determined. 2. In 67 adult male anesthetized rats,...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.2.524

    authors: Kai Y,Oomura Y,Shimizu N

    更新日期:1988-08-01 00:00:00

  • Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.

    abstract::1. Mouse hippocampal neurons in dissociated culture were grown at low density on previously plated hippocampal glial cell cultures and voltage clamped using the tight seal whole-cell patch-clamp technique. Flow pipes were used to rapidly exchange the extracellular solution, and to apply N-methyl-D-aspartic acid (NMDA)...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.2.645

    authors: Mayer ML,Westbrook GL,Vyklický L Jr

    更新日期:1988-08-01 00:00:00

  • Fiber architecture and histochemistry in the cat neck muscle, biventer cervicis.

    abstract::1. Biventer cervicis (BC) is an anatomically complex muscle that is divided by tendinous inscriptions into five in-series compartments of motor units. We have analyzed the fiber architecture and fiber-type composition of these different compartments using microdissection and histochemical methods. 2. BC narrows as it ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.1.46

    authors: Richmond FJ,Armstrong JB

    更新日期:1988-07-01 00:00:00

  • Structure-function relationships in the primate superior colliculus. II. Morphological identity of presaccadic neurons.

    abstract::1. Microelectrodes filled with horseradish peroxidase (HRP) were inserted in the superior colliculus (SC) of alert squirrel monkeys. Spontaneous eye movements were monitored in the dark during recording and intraaxonal injection of fibers carrying presaccadic signals. 2. Analysis of the relationship between neuronal a...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.60.1.263

    authors: Moschovakis AK,Karabelas AB,Highstein SM

    更新日期:1988-07-01 00:00:00

  • Influence of stimulus parameters on human postural responses.

    abstract::1. The role of sensory information in shaping muscle activation patterns to postural perturbations in humans was investigated by varying velocity, amplitude, or duration of the perturbing stimulus. Ten normal subjects were exposed to 120 backward translations of the support surface under conditions of varying velociti...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.6.1888

    authors: Diener HC,Horak FB,Nashner LM

    更新日期:1988-06-01 00:00:00

  • Pharmacological modulation of the rod pathway in the cat retina.

    abstract::1. In the intact cat eye, the responses of ganglion cells to light stimulation were recorded extracellularly and the actions of iontophoretically applied 2-amino-4-phosphonobutyrate (APB), a potent agonist at ON-bipolars, and of strychnine, a glycine antagonist, were investigated. 2. Under light-adapted conditions, th...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.6.1657

    authors: Müller F,Wässle H,Voigt T

    更新日期:1988-06-01 00:00:00

  • Effects of muscle shortening on the responses of cat tendon organs to unfused contractions.

    abstract::1. The discharges from individual Golgi tendon organs of peroneus tertius and brevis muscles were recorded in anesthetized cats. Responses to unfused isometric contractions of single motor units and combinations of motor units were compared with responses to contractions eliciting muscle shortening (i.e., shortening c...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.5.1510

    authors: Horcholle-Bossavit G,Jami L,Petit J,Vejsada R,Zytnicki D

    更新日期:1988-05-01 00:00:00

  • Central peptidergic neurons regulate gut motility in Aplysia.

    abstract::1. The small cardioactive peptides (SCPs) are potent modulatory neuropeptides in Aplysia. Buccal ganglia neurons B1 and B2 are the largest neurons that exhibit SCP-like immunoreactivity. High-pressure liquid chromatography (HPLC)-bioassay and in vivo radiolabeling procedures confirm that these neurons contain and synt...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.5.1613

    authors: Lloyd PE,Kupfermann I,Weiss KR

    更新日期:1988-05-01 00:00:00

  • Direction-selective adaptation in simple and complex cells in cat striate cortex.

    abstract::1. The selectivity of adaptation to unidirectional motion was examined in neurons of the cat striate cortex. Following prolonged stimulation with a unidirectional high-contrast grating, the responsivity of cortical neurons was reduced. In many units this decrease was restricted to the direction of prior stimulation. T...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.4.1314

    authors: Marlin SG,Hasan SJ,Cynader MS

    更新日期:1988-04-01 00:00:00

  • Identification of the physical stimulus and the neural basis of fabric-evoked prickle.

    abstract::1. The neurophysiological basis for the sensation of prickle evoked by contact of some fabrics with the skin is reported. 2. Single-unit sensory nerve recordings from the rabbit saphenous nerve were used to identify the receptors responsible for fabric-evoked prickle. These recordings showed that all low-threshold mec...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.4.1083

    authors: Garnsworthy RK,Gully RL,Kenins P,Mayfield RJ,Westerman RA

    更新日期:1988-04-01 00:00:00

  • The motor-unit population of the cat tenuissimus muscle.

    abstract::1. We studied the organization of motor units in the tenuissimus (TEN) muscle of pentobarbital-anesthetized cats. The cat TEN is a long, delicate straplike muscle that spans hip and knee, which has a very flat length-tension curve through 22 mm of length change. 2. The TEN motor nucleus, labeled by retrograde transpor...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.4.1128

    authors: Lev-Tov A,Pratt CA,Burke RE

    更新日期:1988-04-01 00:00:00

  • Natural groupings of primate spinothalamic neurons based on cutaneous stimulation. Physiological and anatomical features.

    abstract::1. Two hundred and twenty-one spinothalamic tract (STT) neurons in the lumbar spinal cord of anesthetized monkeys were studied. The majority of the recordings were in laminae IV-VI. Thirteen of these neurons were intracellularly injected with horseradish peroxidase and histologically reconstructed. 2. A standard serie...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.3.833

    authors: Surmeier DJ,Honda CN,Willis WD Jr

    更新日期:1988-03-01 00:00:00

  • Slow conductances in neurons from cat sensorimotor cortex in vitro and their role in slow excitability changes.

    abstract::1. The electrophysiological and pharmacological properties of slow afterpotentials in large layer V neurons from cat sensorimotor cortex were studied in an in vitro slice preparation using intracellular recording and single-microelectrode voltage clamp. These properties were used to assess the role of afterpotential m...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.2.450

    authors: Schwindt PC,Spain WJ,Foehring RC,Chubb MC,Crill WE

    更新日期:1988-02-01 00:00:00

  • Electrophysiological evidence from glutamate microapplications for local excitatory circuits in the CA1 area of rat hippocampal slices.

    abstract::1. Evidence for local excitatory synaptic connections in CA1 of the rat hippocampus was obtained by recording excitatory postsynaptic potentials (EPSPs) intracellularly from pyramidal cells during local microapplications of glutamate. 2. Experiments were performed in hippocampal slices cut parallel to (transverse slic...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.1.110

    authors: Christian EP,Dudek FE

    更新日期:1988-01-01 00:00:00

  • Afferent fibers supplying the uterus in the rat.

    abstract::1. In the present three-part study electrophysiological techniques were used to characterize responses of afferent fibers in the rat hypogastric nerve to mechanical or chemical stimulation of the uterus, and anatomical techniques were used to identify the spinal segments through which uterine afferent fibers enter the...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.1.142

    authors: Berkley KJ,Robbins A,Sato Y

    更新日期:1988-01-01 00:00:00

  • The inhibition of cat lateral superior olive unit excitatory responses to binaural tone bursts. II. The sustained discharges.

    abstract::1. Preliminary to extending a point process model of lateral superior olive (LSO) unit activity to describe the units' binaural responses, the statistical properties of their discharges to binaural tone bursts were studied. The hypothesis that stimulation of the contralateral ear results in the simple reduction of the...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1988.59.1.184

    authors: Tsuchitani C

    更新日期:1988-01-01 00:00:00

  • Signal transmission in the catfish retina. IV. Transmission to ganglion cells.

    abstract::1. To characterize the temporal dynamic responses of ganglion cells and to define the possible inputs giving rise to their responses in catfish retina, we recorded the ganglion cell responses evoked by 1) a step of light presented in the dark, 2) an incremental and decremental step from a background illumination, and ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.58.6.1307

    authors: Sakai HM,Naka K

    更新日期:1987-12-01 00:00:00

  • The two-dimensional spatial structure of simple receptive fields in cat striate cortex.

    abstract::1. A reverse correlation (6, 8, 25, 35) method is developed that allows quantitative determination of visual receptive-field structure in two spatial dimensions. This method is applied to simple cells in the cat striate cortex. 2. It is demonstrated that the reverse correlation method yields results with several desir...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.58.6.1187

    authors: Jones JP,Palmer LA

    更新日期:1987-12-01 00:00:00

  • Serotonin and forskolin increase an inwardly rectifying potassium conductance in cultured identified Aplysia neurons.

    abstract::1. The effect of serotonin (5-HT) and forskolin on an inwardly rectifying K+ conductance (IKR) was studied using voltage-clamp techniques in several identified Aplysia neurons isolated and maintained in primary cell culture. 2. Inward rectification was observed in the current-voltage relationship of the identified neu...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.58.5.909

    authors: Lotshaw DP,Levitan IB

    更新日期:1987-11-01 00:00:00

  • Effects of occipital lobectomy upon eye movements in primate.

    abstract::1. Eye movements were recorded before and after bilateral occipital lobectomy in six rhesus monkeys trained to fixate and to follow small targets. Striate cortex was completely removed in two animals; small islands islands remained in the others. In all animals portions of extrastriate cortex were also removed but the...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.58.4.883

    authors: Zee DS,Tusa RJ,Herdman SJ,Butler PH,Gücer G

    更新日期:1987-10-01 00:00:00

  • Effects of hypothalamic stimulation on activity of dorsomedial medulla neurons that respond to subdiaphragmatic vagal stimulation.

    abstract::1. Effects of hypothalamic stimulation on activity of dorsomedial medulla neurons that responded to subdiaphragmatic vagal stimulation were investigated in urethan-anesthetized rats. 2. Extracellular recordings were made from 231 neurons in the nucleus of the tractus solitarius (NTS) that fired repetitively in respons...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.58.4.655

    authors: Nishimura H,Oomura Y

    更新日期:1987-10-01 00:00:00

  • Postnatal development of electrical activity in the locus ceruleus.

    abstract::1. A method for adapting a standard stereotaxic frame for use with neonatal rats as young as postnatal day 1 (PD 1) was devised, and single-unit extracellular recordings were obtained from neurons in the locus ceruleus (LC) in urethan-anesthetized rats during different stages in development from PD 1 to PD 34. 2. The ...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.58.3.510

    authors: Nakamura S,Kimura F,Sakaguchi T

    更新日期:1987-09-01 00:00:00

  • Effect of a spider toxin (JSTX) on excitatory postsynaptic current at neuromuscular synapse of spiny lobster.

    abstract::1. We studied the blocking properties of a spider (Nephila clavata) toxin (JSTX) purified from venom on the spiny lobster neuromuscular junction. 2. When a small amount of JSTX was applied to the neuromuscular junction, the excitatory postsynaptic potential (EPSP) was partially suppressed. The amplitude of EPSPs remai...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.58.2.319

    authors: Miwa A,Kawai N,Saito M,Pan-Hou H,Yoshioka M

    更新日期:1987-08-01 00:00:00

  • The suppressive influence of moving textured backgrounds on responses of cat striate neurons to moving bars.

    abstract::The suppressive action of a moving textured background on responses to moving bars was investigated in 118 striate neurons, 19 dorsal lateral geniculate neurons, and 5 perigeniculate neurons in paralyzed and anesthetized cats. In standard conditions the background was a two-dimensional (2D) noise pattern, the bar move...

    journal_title:Journal of neurophysiology

    pub_type: 杂志文章

    doi:10.1152/jn.1987.57.6.1767

    authors: Gulyás B,Orban GA,Duysens J,Maes H

    更新日期:1987-06-01 00:00:00

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